This is your brain on drugs. Or rather, the right-hand image is your brain on psilocybin. The other side is your brain on a non-psychedelic drug. Researchers recently discovered some amazing facts about how our brains work on some chemicals. And some psychedelic drugs prove to have pretty amazing effects. But don’t try this at home… stick to building toy rockets and drones for your science experiments…
Apparently Timothy Leary was right: psychedelic drugs change the way users think. For a long time, possibly forever. In his pioneering work, The Psychedelic Experience (1964), Leary wrote
A psychedelic experience is a journey to new realms of consciousness. The scope and content of the experience is limitless, but its characteristic features are the transcendence of verbal concepts, of space-time dimensions, and of the ego or identity. Such experiences of enlarged consciousness can occur in a variety of ways: sensory deprivation, yoga exercises, disciplined meditation, religious or aesthetic ecstasies, or spontaneously. Most recently they have become available to anyone through the ingestion of psychedelic drugs such as LSD, psilocybin, mescaline, DMT, etc. Of course, the drug does not produce the transcendent experience. It merely acts as a chemical key — it opens the mind, frees the nervous system of its ordinary patterns and structures.
He also said in a 1966 CBS documentary about his work,
We always have urged people: Don’t take LSD unless you are very well prepared, unless you are specifically prepared to go out of your mind. Don’t take it unless you have someone that’s very experienced with you to guide you through it. And don’t take it unless you are ready to have your perspective on yourself and your life radically changed, because you’re gonna be a different person, and you should be ready to face this possibility.
A story in Wired Magazine about this new research described the image above:
A representation of that is seen in the image above. Each circle depicts relationships between networks—the dots and colors correspond not to brain regions, but to especially connection-rich networks—with normal-state brains at left, and psilocybin-influenced brains at right…
In mathematical terms, said Petri (study co-author Giovanni Petri, a mathematician at Italy’s Institute for Scientific Interchange), normal brains have a well-ordered correlation state. There’s not much cross-linking between networks. That changes after the psilocybin dose. Suddenly the networks are cross-linking like crazy, but not in random ways. New types of order emerge…
Petri notes that the network depiction above is still a simplified abstraction, with the analysis mapped onto a circular, two-dimensional scaffold. A truer way of visualizing it, he said, would be in three dimensions, with connections between networks forming a sponge-like topography.
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