Someone is wrong on the internet


From Skeptic NorthI discovered an entertaining site recently called Skeptic North. It’s a Canadian equivalent to several similar sites and blogs I read that are mostly American-based. It challenges popular assumptions, ideas, trends and pseudoscience and other claptrap. In a Canadian way, of course.

Meaning that it’s usually much too polite in how it handles some of the balderdash online. I’m less gracious. Bullshit is bullshit and should be called out.

I discovered it when I was looking for some additional backup material on COLD FX, an over-the-counter, made-in-China product (I hesitate to call it a medicine; is pseudo-medicine a proper word? or should I just call it a commercial placebo?) made from a purified ginseng extract, that claims to boost your immune system and prevent colds and flus. The discussion has raised itself on Facebook again, with the usual “I don’t care what scientists say, it works for me…” comments.

CBC’s Marketplace show did a’ expose that debunked a lot of the claims, but I found the show a little too sensationalist for my own taste. I was glad to see the article on Skeptic North about the show shared my concerns over the presentation*.

…I was turned off by the typical “confrontation TV” drama they included.

The effectiveness of Cold FX has been debated and challenged long before CBC got around to it. UBC professors questioned it back in 2006. They found:

The main purpose of these studies was to see whether the ginseng extract would reduce the incidence of acute respiratory illnesses (flu and respiratory syncytial virus, or RSV, a virus that causes flu-like symptoms), as defined by subjective symptoms such as cough, sore throat and runny nose. The researchers, reporting the results in the Journal of the American Geriatrics Society, found “no significant difference between the placebo and the ( Cold-fX) groups for the number of (acute respiratory illnesses) defined by symptoms.” They also found “no significant difference in the severity or duration of symptoms related to (acute respiratory illnesses) between the two groups in either study.”

The secondary purpose of the studies was to measure the difference in the incidence of laboratory-confirmed (typically by a viral culture) acute respiratory illnesses between the two groups. In the placebo groups, six and 12 per cent of the subjects in the two studies contracted flu or respiratory syncytial virus. In the ginseng groups, these percentages were lower — zero and two per cent — which suggests the ginseng had some therapeutic benefit. However, in each case, the “p value” — the probability that chance explained the difference — was high enough that these differences, by the researchers’ own admission, were not deemed statistically significant.

In 2009, Science-Based Pharmacy published the results of three studies that challenged the product’s claims. Here are the results from the three studies:

Bottom line: If we accept the combining of the two trials, we can conclude the following: In nursing home residents, when taken for 8 to 12 weeks, Cold-fX appeared to reduce laboratory-confirmed cases of colds and flu, but had no effect when considering what patients actually reported.

Bottom line: A healthy adult taking Cold-fX might expect to have 0.25 less colds over a 16 week period. This has led some to question whether this result is clinically relevant.)

Bottom line: Over a 16 week period Cold-fx failed to demonstrate an improvement over placebo. Given the high number of study design flaws, data omissions, the poor quality journal, and long publication delay, it is difficult to draw conclusions from the results. At best, it is suggestive that Cold-fX needs to be taken for at least eight weeks, with a flu shot after four weeks, before it may have any noticeable effect.

And the conclusion in the article?

What if I feel like I’m coming down with a cold? Will starting Cold-fX now have any effect?

There is no published evidence to demonstrate the effectiveness of Cold-fX if started at the onset of a cold.

CV Technologies offers a 300mg form of their product (“Extra-Strength Cold-fX“) with the directions to start “at the first sign of colds of flu symptoms”. There are no published trials documenting the effectiveness of the 300mg dosage strength, or evaluating the dosing instructions of 12 capsules over the first 3 days, in reducing the duration of colds or the flu.

The Ottawa Skeptics site also has a good article critiquing how the studies are presented, and says, for example,

Although this trial was well designed, reviewers have criticized the interpretation of the results. For example, the study team described the combined reduction in lab-confirmed influenza and respiratory syncytial virus (RSV) as “an overall 89% relative risk reduction”[22] (i.e., an 8% reduction compared to a 9% incidence rate), which is true but misleading. In reality, there was simply an absolute risk reduction of 8% points.

Claims that COLD FX has approval for its packaging statements have also been challenged, as this National Post article notes:

Health Canada has not authorized COLDfX’s long-standing claim that consumers can obtain “immediate relief” from colds and flu by dramatically increasing the dosage, the Vancouver Sun has learned.

You can read the company’s own comments about their battle over claims with Health Canada in 2007, here. Back then, the Center for Science in the Public Interest, a well-respected organization, cautiously noted that,

Bottom line: Until more studies are done, it’s too early to conclude that Cold-fx can shorten—or cut your odds of catching—a cold or the flu. Even so, Cold-fx is the only remedy we found with any evidence that it might improve your chances of getting through the cold and  flu season without coming down with something.

This lukewarm endorsement has not been repeated since  to my knowledge (I subscribe to their excellent newsletter, Nutrition Action). In general, CSPINET has been critical of all herbal remedies and done a lot of work researching their claims and effectiveness (which generally is none). Nonetheless, some of the claims made by COLD FX have been the subject of a recent class-action lawsuit, which, as far as I know, is still being decided.

It’s curious to me that people who swear by COLD FX and other non-medicinal products like echinecea - another herbal product proven ineffective – yet will not get a flu shot, which is backed up by considerable research and science and endorsed by every national and provincial health organization and medical association in Canada and the USA. COLD FX is endorsed by Don Cherry. Which do you believe is the more credible? As The Paltry Sapien blogger (another entertaining skeptic) wryly comments.

We like to talk about science and proof and rationality, but in the end belief in hockey and maple leaves and the coldness of winter wins out. Cold FX, this “struggling true-blue Canadian company,” in Cherry’s words — producing a product in China, not Alberta — deserves our allegiance.

Flu shots are free in Canada. COLD FX is expensive (emphasis added):

Over a four-month period, subjects in the ginseng group experienced, on average, one-quarter of a cold less than the placebo group. That means each person has to spend a total of $86 to prevent one-quarter of a cold.

I ascribe a lot of this to the New Age belief that so-called “natural” products (a nebulous term of little value, like “organic,” both degraded by slippery definitions, lax regulations and unscrupulous marketers and – ironically – corporations) are better than manufactured ones. That counterintuitive leap has extended into all sorts of silliness, from belief in astrology and Feng Shui to crystal therapy and magnetic bracelets over astronomy,  architecture, science, and medicine. And let’s not forget UFO abductions, creationism and the Mayan apocalypse – or flu-shot paranoia.

I have yet to find an all-natural computer or iPad on which I can post that observation.

But as for these herbal concoctions – many people want a pill to do for them what they would better get from proper hygiene (frequent hand washing), good nutrition and exercise – without having to do all the work. It’s like the herbal-diet-fat-burning pills: instant gratification without the sweat. Won’t happen.

~~~~~

* For the sake of balance, not everyone thinks the CBC Marketplace show was either accurate or good journalism. For example, blogger Shireen Jeejeebhoy says,

By the end of the twenty-two-odd minutes, Marketplace’s entire piece, when read between the lines and engendering Herculean effort not to be distracted by the bells and whistles, boils down to COLD-FX prevents colds. The claim it provides immediate relief needs further study; the China connection is no different than every other product we buy (have you checked where your frozen veggies are grown lately?), thus is not COLD-FX specific and is a separate topic; the bacterial contamination is old news and a non-starter. In other words, Marketplace told its alert viewers to take COLD-FX daily if you want to prevent colds.

426 total views, 3 views today

Are internet polls valid?


Internet pollHow valid are internet polls? Are they credible for making serious or significant decisions, or merely as general – even vague – indicators of intent? Are they equivalent to paper (and phone) surveys?

No. At least that’s what many experts say. Yes, they can be cost-effective, and good tools to engage the community. But like online petitions, they seldom have sufficient controls that restrict access to the relevant respondents. Anyone with a basic knowledge of how the internet works can easily bypass the limited security and vote numerous times. Often all it takes to get another vote is deleting cookies in your browser tools. More sophisticated users can create voting bots that automate the process.

Time poll hackedYou can read many articles on how to easily hack polls and cheat them. Some poll hacking is actually quite entertaining and imaginative, like the hack of the 2009 Time poll on the most influential people. The point is that polls are vulnerable to a variety of techniques. As one programmer noted about the Time poll:

“I took a look at the process of voting with a very basic set of tools on Firefox: Firebug and LiveHTTPHeaders. What I found is that when you submit the rating, it calls another page and passes a key, the rating, and the poll information through the URL to the page, like so:

http://www.timepolls.com/contentpolls/Vote.do?key=eba3a55e955bc93ade4fc820649cde04&rating=9&id=1857552&pollName=poy2008

Theoretically, then, you could hit this page as many times as you wanted with any rating you wanted, and drive up a candidates’ score. Though one would expect that Time would have figured that anyone could game the system, it’s easy for a programmer to forget that what they don’t intend for public viewing may still be visible, and that they always need to check to ensure that the data they expect is the data they are getting.”

Generic online polls are easy to create and many are free – this makes them attractive to businesses, media and political groups that don’t have the resources to do phone or door-to-door surveys. How many of these instant polls are actually mining participant data can’t be determined, but you have to expect the companies to get some return for a “free” service. Some media clearly use polls not as a count of anything specific, but rather as a measure about how engaged people are on an issue – and how much attention they are paying to that particular media’s coverage of it.

As one Australian study concluded,

“…online polls cannot be considered as an alternative to using paper based surveys. The independent sample t-tests results obtained for the questions administered using a paper based survey and those through an online poll showed that in the majority of cases that there was significant difference between the means. The implication is that online polls cannot be used to survey a cohort of people replacing the more costly paper based survey.

Online polls and surveys are generally open to anyone with an internet connection. Similar to clicking the Facebook “like” button, most online polls simply count clicks, but don’t qualify them by demographic – gender, region, sex, age, income or anything else that might matter. While some may believe 12 and 13-year-olds should be able to vote for any issue, they are not really old enough to appreciate the many facets of any political or social issue. But how do you tell if a vote was cast by a child or an adult?

Unless you have qualifying questions that ask personal information to identify the participant as belonging to the target demographic you need, you can’t distinguish between valid and invalid votes. That makes them all invalid.

Everyone on Facebook knows that the count of “likes” is irrelevant because Facebook lacks a corresponding “dislike” button to provide balance. Without that, the number of likes or followers has to be measured against Facebook’s almost one billion subscribers. Having 1,000, even 100,000 “likes” is a small percentage of the total possible. But even with millions, you have no way of qualifying those “likes” by any meaningful categorization. Yes, Facebook can do it, but they’re not giving the important data to users free. Besides, when it comes down to it, “likes” may make the user feel better and more popular, but they don’t add up to much else than self-importance.

It used to be the count of page hits that people boasted about. That quickly ended when website owners started putting “counters” on pages that faked the numbers, or started with high numbers. To get a real picture of website use today you need sophisticated tools like Google Analytics that identify time spent per page, whether the page was visited by a search bot or a human, whether the user went to other linked pages within that site, the search terms used to land on that page, etc. Online surveys without that sort of statistical analysis are much like the old page count numbers of the 1990s.

Some online petitions and polls even allow the same person to digitally “sign” or vote more than once. Some petitions allow participants to be “anonymous” to others (which clearly defeats the purpose of a petition as a tool of democracy). Again, that opens questions about validity and credibility. Anonymous online comments or petition signatures have no credibility in the democratic process.

Because these petitions invite comments, it’s not uncommon for people to use them as sounding boards for comment and griping, rather than for their intended purpose of gathering support for a particular position. Bitching about the state of government may be stress-relieving, but it is not relevant to the petition and dilutes the intended message.

Any online petition has to be carefully combed for duplication and repetition of names. Even once these are winnowed out, how can anyone determine the age or location of the signatory unless that information is required when signing and provided as part of the presentation? How do the presenters insure the remaining names are valid in respect to the subject of the petition? This is one reason why paper petitions still have considerably more validity than online ones.

Crazy pollsI have voted in online polls and surveys about American politics and presidential races. I’m a Canadian so my vote, my choices should be meaningless, yet there were no qualifying questions posed to restrict access to Americans of voting age. What if the Chinese government took a serious interest in the American presidential race and used US online polls to sway the results towards Chinese goals? Why not? If a poll by one of the two parties asked whether the US Army should be disbanded, wouldn’t it be in the national interests of, say, Iran, China, North Korea, Russia or Syria to push the poll numbers up towards yes and get that onto the candidate’s platform?

Could US policy be shaped by such polls? Not yet. At present there’s a good level of skepticism about online polls among politicians and their strategists. Making a claim that “70 percent of Americans want to disband the army” based on an internet poll would be not only incorrect, but stupid.

Similarly, if we run a poll asking if school should be two hours shorter and we get 12,000 yes votes, and 3,000 no, should school boards seriously consider reducing school hours? What if you found out 11,000 of those yes votes were cast by students under the age of 18? Would that affect how the poll was perceived by educators and administrators? Of course. Qualifying data is always necessary to validate the results.

Have an opinion on something? Anything? There are

On Sodahead, a popular opinion site, here’s the latest series of polls you can vote on, taken from the front page:

Do Father-Daughter Dances Promote Gender Discrimination?
Arnold Schwarzenegger Releases Book Trailer: Are You Interested in Reading His Memoir?
Will J.K. Rowling Find Success Beyond ‘Harry Potter’?
New Studies Cite Stronger Link Between Soda and Obesity: Do You Drink Soda?
KFC Closes Restaurants in Pakistan Amid Protests: Should U.S. Retailers Get Out of the Middle East?
Is Vogue Featuring Domestic Violence On Its Cover?
Which Show Are You Rooting for to Win the Emmy for Best Comedy Series?
Are Celebrity Video Games Awesome or Annoying?
Which News Anchor is Least Likely to Lie to Viewers
What were you most excited to leave behind after high school?
Do You Multitask at the Movie Theater?
Does Kanye West Have a Sex Tape?
Are These GPS Shoes Wonderful or Weird?

Perhaps it’s just me, but whenever I visit this site, I keep asking myself “Who cares?” Were these questions created by bored 15-year-olds? Any number of irrelevant, pointless, puerile polls are available online to people who want to express an opinion, but face it: the results aren’t going anywhere because NO ONE CARES about the results. They’re just there to make you feel engaged, let off steam, and think you’ve contributed to something.

For any opinion poll to be valid, it needs to meet certain crucial scientific criteria, including sample size. Most online polls don’t meet any serious selection criteria at all, which means they’re simply for entertainment, like horoscopes.

What is a valid sample size that gives a result meaning? One percent? Ten? Twenty five? What is the effective sample size for, say, Collingwood, with a population of 20,000?

Let me quote at length from an answer on how polls have to be conducted and what sort of sample size is relevant:

You have a two part question – but you didn’t realize it. The question, which you asked, is: “What should my sample size be for this test?”

If you go to the Sample Size Calculator website (www.berrie.dds.nl/calcss.htm), you can find this:

The parameters you are setting are:
1) Population – the number of people in the world who will be seeing your website. Let’s assume that your population is “everyone in the world.” So, if we use a very large number, say, 1,000,000, we will calculate the maximum sample size needed.
2) Confidence - this is how sure you are going to be that the results of your sample reflect the true population. The higher the number, the larger the sample size. This is the “certainty” of the results. Customarily for most marketing work, 95% confidence is ample. The default in the website is set at 0.95.
3) Margin – This is how much error you are willing to allow. If you allow 5% error, that means that in a sample size of 100, if the results are 50 clicks, the true number of clicks could be between 45 and 55 clicks. This is the “precision” of your test. The small this number, the larger the sample size.
4) Probability - this is the value of the result you expect to get. For instance, if you expect to get 50 clicks out of 100 views, this value is set at 0.5. Of course, most of us don’t know this value. But the good news is that setting it at 0.5 yields the largest sample size. If the number of clicks is 20 or 80, the confidence increases for the same margin or the margin decreases for the same confidence. And this is a good thing.

Sample size, of course, determines cost of the test. In your case, this is time. If we use the parameters of a population of 1,000,000 with 95% confidence for 5% margin of error with a probability of 50%, then the sample size is 385. For a 1% margin, it’s 9517. You are at about 1.45% now. That means that you are within 65 of the true population result. Additionally, assuming the number of views are pretty close, this means that if the results of your test can tell the difference between the two websites as long at the results are different by more than 65.

The second part of the question – that you didn’t ask – is how do I determine if the two results are really different. For this, you do another test – a Chi-squared test. You have a hypothesis that the two results are the same versus the alternative that they are different. For the test, we look at the observed values versus “expected values.” Expected values are what we’d get is we added the total clicks for both tests and divided by total views and then multiplied by the views for each:

3760/9060 = 0.415
Expected values
4550 * .415 = 1888
4510 * .415 = 1872

Divide the difference of the expected values squared by the expected value and add the two values:

(2010 – 1888)^2/1888) = 7.883
(1750 – 1872)^2/1872) = 7.951

Sum is 15.834. Using a Chi-square table like at: http://www.richland.edu/james/lecture/m170/tbl-chi.html

If we set our confidence at 95%, we use 1 – .095 = 0.05. Our degrees of freedom are calculated by subtracting 1 from the number of proportions in our test: 2-1=1. So, for 95% confidence, we test the value of 15.834 against 3.841. Since 15.834 is larger, we reject our hypothesis that the two results are the same and accept the alternative hypothesis that they are different – with a much greater than 95% confidence.

So, as Nelson (nelsonm) stated in about 20% of the space, you’re done. Looks like version A is the best with a greater than 95% confidence.

Using the sample size calculator mentioned above, here’s what I calculate for a reasonably accurate survey for Collingwood. Based on a population of 20,000, a confidence level of .95, margin of .05, and probability of .50, the minimum sample would be 378 to get a reasonably accurate assessment.

That’s a fairly small number. But how can one determine the numbers to be punched into the various parts of the equation? What’s the confidence level, margin of error? Change the margin of error to 0.01 – a mere 1% error of margin – then you need a sample size of 6,491. Which number do you change to account for duplicates, outside (irrelevant) votes or votes made by children?

And let’s not be fooled: online polls can be and have been the target of special interest groups who want to express their own agenda. Election polls are particularly vulnerable to this sort of nefarious activity.

Journalists have to be particularly suspicious of online polls. The National Council on Public Polls (NCPP) provides 20 questions a journalist should ask about poll results. Among these is:

How were those people chosen?
The key reason that some polls reflect public opinion accurately and other polls are unscientific junk is how people were chosen to be interviewed. In scientific polls, the pollster uses a specific statistical method for picking respondents. In unscientific polls, the person picks himself to participate.

In other words, self-participation is unscientific. A bit further down the page, it notes,

But many Internet polls are simply the latest variation on the pseudo-polls that have existed for many years. Whether the effort is a click-on Web survey, a dial-in poll or a mail-in survey, the results should be ignored and not reported. All these pseudo-polls suffer from the same problem: the respondents are self-selected. The individuals choose themselves to take part in the poll – there is no pollster choosing the respondents to be interviewed.

Governments cannot govern by poll. That’s not leadership. But attempting to govern by internet poll is not merely foolish but potentially dangerous. There is little if any way to determine the source of the votes. You might as well govern by magic ball or coin toss.

So when I read a statement like, “A community poll has shown that 7 out of 10 residents support the one community centre concept” I have to ask, who did the poll, where, when and how was it conducted? That statement turns out to be based on the results of an Enterprise-Bulletin online poll, which had approximately 200 results – 200 unqualified, unscientific results. As pointed out in the quote above, a sample size for Collingwood to get a reasonable assessment of public opinion would be at least 378 QUALIFIED votes. Qualified means a resident or taxpayer, of majority age, who understands the question being posed.

Ipsos-Mori research
Who conducts the poll and who provides the results is also important. Voters on the left don’t trust polls produced by voters on the right and vice versa. Some media are trusted to be objective, others – Fox and Sun News, for example – will always be suspected of having a bias towards their particular political slant. And the majority doesn’t trust the government to accurately and objectively present figures.

My final point has to do with the questions themselves. Asking “Do you like ice cream?” is asking for a general personal opinion and really doesn’t need more choices than “Yes, No, Sometimes.” A more specific question would be, “Do you like butterscotch ice cream?” Ice cream manufacturers are not going to change their business plans based on these rather vague questions, however. They might pay more attention to a question asking participants to select from a list of flavours not currently made, but one which they would like to see available.

Asking “Should we build a new town hall?” is an iceberg question: it hides a larger mass of questions below it: “What will it cost?”, “Will it raise my taxes?”, “Who will benefit?”, “Why do we need one?”, “Can the old town hall be refurbished?”, “when will it be built?,” “where will it be built?”and so on. Participants need answers to all those hidden questions before they can properly answer the seemingly simple question posed about building a new town hall. Otherwise, the answers on that poll are essentially meaningless.

A more reliable question might be, “Should we build a new town hall on the western side of town away from other municipal services, if it will take five years, disrupt some municipal services during construction, cause intermittent road closures, raise your taxes by 10% a year, have it located at the edge of town, result in hiring more staff, and incur greater operating costs when it opens, despite staff recommendations that we just refurbish the old one?”

Even that doesn’t include all of the factors necessary in the decision making process: what to do with the old town hall, should local contractors get preference in the tendering process, will there be local jobs created, can we get support funding from other governments, is the building “green” or LEEDS certified, do we have to buy or expropriate property, is the site currently zoned for it?

Most of all it doesn’t answer the biggest question: why do we need one now?

Perhaps, if you can vouchsafe that the participants in your poll have all paid close attention to the debate about building a new town hall, that they have attended council meetings to watch the debates, have read all the staff reports, have listened to the treasurer expound on the financial implications, have read and watched the local media to gain insight and understand the differences of opinion – they might be able to answer “Should we build a new town hall?” without further refinement. Good luck finding enough people in that category to fit the necessary sample size to validate the results.

Even if you could find such a group, the results can’t simply be reported in terms of yes and no votes. Demographic breakdown of the results is important, too. Politicians should be told the geographic location of the participants (how many west-end participants voted no compared to the east-end, for example), their age groups (are working parents more in favour than retirees?), gender, whether they live in town full-time or part-time, whether they own a vehicle or use public transit to get around town – all become parts of the decision-making milieu.

Most internet polls are merely for entertainment purposes. They harmlessly allow us to believe we are being engaged and are participating in the process, and they make pollsters happy to receive the attention. They are, however, not appropriate tools for making political or social decisions unless they are backed by rigid, scientific and statistical constraints.

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The lingering wisps of memory, the subtle newness of a moment…


Hippocampus“Can the simple act of recognizing a face as you walk down the street change the way we think?” Thus opens a story posted on Science Daily. “Or can taking the time to notice something new on our way to work change what we remember about that walk?”

Intriguing questions. The act of recognition, the act of discovery; both can change how we both process information about an act, and how we create a memory of it.

This novel finding suggests that our memory system can adaptively bias its processing towards forming new memories or retrieving old ones based on recent experiences. For example, when you walk into a restaurant or for the first time, your memory system can both encode the details of this new environment as well as allow you to remember a similar one where you recently dined with a friend. The results of this study suggest that what you did right before walking into the restaurant can determine which process is more likely to occur.

Does this mean that we can train ourselves to remember an event or an activity better by planning to notice things? Or by actively looking for something familiar? But remembering and retrieving, while they are both controlled by the hippocampus, they are competitive processes.

Previous scholarship has demonstrated that both encoding new memories and retrieving old ones depend on the same specific brain region — the hippocampus. However, computational models suggest that encoding and retrieval occur under incompatible network processes. In other words, how can the same part of the brain perform two tasks that are at odds with each other?
At the heart of this paradox is distinction between encoding, or forming a new memory, and memory retrieval, or recalling old information. Specifically, encoding is thought to rely on pattern separation, a process that makes overlapping, or similar, representations more distinct, whereas retrieval is thought to depend on pattern completion, a process that increases overlap by reactivating related memory traces.

To take advantage of this would require people to be very alert and aware, all the time, not by accident or coincidentally – as in the recognition of a familiar face encountered in a walk. In his masterwork, Walden (Chapter Two), Henry David Thoreau wrote,

Why is it that men give so poor an account of their day if they have not been slumbering? They are not such poor calculators. If they had not been overcome with drowsiness, they would have performed something. The millions are awake enough for physical labor; but only one in a million is awake enough for effective intellectual exertion, only one in a hundred millions to a poetic or divine life. To be awake is to be alive. I have never yet met a man who was quite awake. How could I have looked him in the face?
We must learn to reawaken and keep ourselves awake, not by mechanical aids, but by an infinite expectation of the dawn, which does not forsake us in our soundest sleep. I know of no more encouraging fact than the unquestionable ability of man to elevate his life by a conscious endeavor. It is something to be able to paint a particular picture, or to carve a statue, and so to make a few objects beautiful; but it is far more glorious to carve and paint the very atmosphere and medium through which we look, which morally we can do. To affect the quality of the day, that is the highest of arts. Every man is tasked to make his life, even in its details, worthy of the contemplation of his most elevated and critical hour. If we refused, or rather used up, such paltry information as we get, the oracles would distinctly inform us how this might be done.

Why is it that seeing one thing can trigger your awareness so that you notice other things, often completely unrelated to the first item?

“We’ve all had the experience of seeing an unexpected familiar face as we walk down the street and much work has been done to understand how it is that we can come to recognize these unexpected events,” said Lila Davachi, an associate professor in NYU’s Department of Psychology and the study’s senior author. “However, what has never been appreciated is that simply seeing that face can have a substantial impact on your future state of mind and can allow you, for example, to notice the new café that just opened on the corner or the new flowers in the garden down the street.”

The same face, the same building, the same tree seen at different times can trigger different responses. One day it might be surprise, another nostalgia, another indifference, and another anger. Why? Perhaps it’s because your brain is busily storing and retrieving all sorts of data, and on the way in or out, the pattern triggers other neurons that activates the emotional activity.

But why or how did this trait evolve? Is it a defence mechanism; something we needed when we came out of the forests into the open plains of Africa? Or is it something older, something from our reptilian past?

Does the same mechanism for memory and awareness affect animals? Dogs and cats, for example, have memories. But can they consciously control their awareness (which raises the question about whether animals are self-aware, to which I reply, yes, but how much awareness they can manipulate remains open to debate).

Another researcher added:

“We spend most of our time surrounded by familiar people, places, and objects, each of which has the potential to cue memories,” added Katherine Duncan, the study’s first author who was an NYU doctoral student at the time of the study and is now a postdoctoral researcher at Columbia University. “So why does the same building sometimes trigger nostalgic reflection but other times can be passed without notice? Our findings suggest that one factor maybe whether your memory system has recently retrieved other, even unrelated, memories or if it was engaged in laying down new ones.”

I remain fascinated by the development of these models of consciousness and the inner workings of neuroscience.

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Super-fast evolution: new species in just 6,000 years


Sea starsAccording to a recent story in Science Daily, new species of sea stars may have arisen in as little a time as 6,000 years.

Researchers studied the diversity in DNA sequences from sea stars of two related species to estimate how long it has been since the two species diverged. Their results showed a range from roughly 6,000 to 22,000 years ago.

That rules out some ways new species could evolve. For example, they clearly did not diverge slowly with genetic changes over a long period of time, but were isolated quickly.

Over the last 11,000 years, the boundary between cold and warm water in the Coral Sea has fluctuated north and south. A small population of the ancestral sea stars, perhaps even one individual, might have colonized a remote area at the southern end of the range then been isolated by one of these changes in ocean currents.

These two species of “cushion stars” – Cryptasperina pentagona and C. hystera – while they look very similar, are very different in many aspects – habitat and sex lives in particular.

Pentagona has male and female individuals that release sperm and eggs into the water where they fertilize, grow into larvae and float around in the plankton for a few months before settling down and developing into adult sea stars.
Hystera are hermaphrodites that brood their young internally and give birth to miniature sea stars ready to grow to adulthood.

Six thousand years is a remarkably short time for a significant evolutionary activity – about the entire length of recorded human history. And about as long as some creationist crackpots think the Earth has been in existence. But it’s not a one-speed-fits-all for evolutionary change. Even the longer 22,000 years is still remarkably short. That’s about when the first Europeans arrived in North America, or the length of the time it takes the remarkable planetoid, 2006 SQ372, to complete its orbit.

Earlier this year, Wired Magazine published a story about research to discover how long it would take for a mouse-sized animal to evolve to an elephant-sized one. And the answer was 24 million years.

That’s how many generations a new study estimates it would take to go from mouse- to elephant-sized while operating on land at the maximum velocity of change. The figure underscores just how special a trait sheer bigness can be.
“Big animals represent the accumulation of evolutionary change, and change takes time,” said evolutionary biologist Alistair Evans of Australia’s Monash University.
Evans and co-authors revisit a fossil record dataset of mammal body size during the last 70 million years, in a study published Jan. 31 in Proceedings of the National Academy of Sciences. The data was originally used to describe the evolutionary growth spurts experienced by mammals soon after dinosaurs ceased to be Earth’s dominant animals.
The relative sizes of mouse and elephant skulls. To go from mouse-sized to elephant-sized would take at least 24 million generations.
For the previous 140 million years, mammals had been rat-sized or smaller. With dinosaurs significantly reduced, mammals had a chance to fill newly vacant ecological niches, particularly that of the large-bodied plant-eater.

But what about human evolution? We have a pretty good record of our species’ evolution over more than 4 million years, from the apelike Ardipithecus through Australopithecus, Neanderthal, Cro Magnon to us. But we are, like other animals, still evolving. And the rate of evolution may be speeding up.

According to a story in National Geographic,

Explosive population growth is driving human evolution to speed up around the world, according to a new study.
The pace of change accelerated about 40,000 years ago and then picked up even more with the advent of agriculture about 10,000 years ago, the study says.
And while humans are evolving quickly around the world, local cultural and environmental factors are shaping evolution differently on different continents.
“We’re evolving away from each other. We’re getting more and more different,” said Henry Harpending, an anthropologist at the University of Utah in Salt Lake City who co-authored the study.
For example, in Europe natural selection has favored genes for pigmentation like light skin, blue eyes, and blond hair. Asians also have genes selected for light skin, but they are different from the European ones.
“Europeans and Asians are both bleached Africans, but the way they got bleached is different in the two areas,” Harpending said.
He and colleagues report the finding this week in the journal Proceedings of the National Academy of Sciences.

And some birds may be evolving faster, too – depending on their colour. According to a story in Science Daily in May,

Researchers have found that bird species with multiple plumage colour forms within in the same population, evolve into new species faster than those with only one colour form, confirming a 60-year-old evolution theory.
The global study used information from birdwatchers and geneticists accumulated over decades and was conducted by University of Melbourne scientists Dr Devi Stuart-Fox and Dr Andrew Hugall (now based at the Melbourne Museum) and is published in the journal Nature.
The link between having more than one colour variation (colour polymorphism) like the iconic red, black or yellow headed Gouldian finches, and the faster evolution of new species was predicted in the 1950s by famous scientists such as Julian Huxley, but this is the first study to confirm the theory.
By confirming a major theory in evolutionary biology, we are able to understand a lot more about the processes that create biodiversity said Dr Devi Stuart-Fox from the University’s Zoology Department.

So much science, so much research that continues to prove Darwin’s original theory, albeit much refined today thanks to our genetic research. You have to wonder, then, why 46% of Americans and 42% of Canadians and many others in the world still believe in the nonsense of creationism nor the pseudoscience of “intelligent” design.

I blame the continued survival of creationism on our failing education system with its lack of emphasis on science and its lack of training in critical thinking; on our society’s growing distrust in and disrespect for intellectuals; and the increasing influence of fundamentalist religion in politics.

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The Tin-Foil Hat Brigade in the Lab


Tin Foil hatsYou have to admire science. Nothing is beneath its inquiring eye. When I read that students at Berkley U had seriously investigated the nature of the ubiquitous-in-the-wingnut-community tin foil hats, I had to smile. Once again, science saves the day.

Bad news for the wingnuts. While research didn’t prove tin foil hats will stop the aliens from eating your brain, it did suggest that the hats may amplify certain frequencies that may be in the control of either governments or corporate interests.

According to the researchers at berkeley.intel-research.net/arahimi/helmet/,

The helmets amplify frequency bands that coincide with those allocated to the US government between 1.2 Ghz and 1.4 Ghz. According to the FCC, These bands are supposedly reserved for ”radio location” (ie, GPS), and other communications with satellites (see, for example, [3]). The 2.6 Ghz band coincides with mobile phone technology. Though not affiliated by government, these bands are at the hands of multinational corporations.

Then with what can only be tongue-in-cheek seriousness, the authors of the study conclude,

It requires no stretch of the imagination to conclude that the current helmet craze is likely to have been propagated by the Government, possibly with the involvement of the FCC. We hope this report will encourage the paranoid community to develop improved helmet designs to avoid falling prey to these shortcomings.

Gawds, I love this sort of thing. Unfortunately, the video of the research and results has been taken off YouTube. I can only hope someone restores it.

In the mean time, any creationists or self-described psychics among my readers should be concerned that your tin foil hats are actually allowing the evil government spy agencies access to your thought waves… better turn on the microwave to scramble their signals…

Thanks to Haggle for posting the link!

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Having a purpose strengthens your brain


Cartoon StockA story in Science Daily caught my eye recently. It was titled, “Greater Purpose in Life May Protect Against Harmful Changes in the Brain Associated With Alzheimer’s Disease.” That suggested a different approach to brain ailments than what I’ve usually read. Most are medical or surgical. This one is philosophical.

I’m not one for either self-help or New Age palaver. Most of it strikes me as unmitigated pap that borders on the religious. It’s like the gazillions of diet books and websites. I’m not sure which would rake in the millions faster: to form a new religion or a new diet plan.So when I see something about a “purpose-driven life” I tend to shy away in case it involves angels, spirit guides, auras, ghosts or ten people you’ll meet in heaven. Or hell.

But when someone in the science community comments that purpose has more use than filling one’s days or creating fodder for self-help gurus, that it may have medical and biological implications, then I perk up and listen.

“Our study showed that people who reported greater purpose in life exhibited better cognition than those with less purpose in life even as plaques and tangles accumulated in their brains,” said Patricia A. Boyle, PhD.
“These findings suggest that purpose in life protects against the harmful effects of plaques and tangles on memory and other thinking abilities. This is encouraging and suggests that engaging in meaningful and purposeful activities promotes cognitive health in old age.”

In other words, as I read it: purpose makes you think better. Well, council watchers may want to debate that issue.

I know people today, including many people younger than I am, who don’t read to exercise their brains, don’t play interactive games (like chess, go, bridge), don’t do anything creative as a hobby (like write, play music, garden, take photographs). They work, they watch TV, they sleep. TV – a passive device programmed by media giants who want to control your life and consumer habits – is their main source of information, entertainment, opinion and education. What sort of purpose in life does watching TV fulfill?

By the terms of this study, they’re dementia patients in the making. Anyone who wastes hours of their life watching such dreck as “Survivor” or “American pickers” probably won’t notice the onslaught of dementia…

Boyle and her colleagues from the Rush Alzheimer’s Disease Center studied 246 participants from the Rush Memory and Aging Project who did not have dementia and who subsequently died and underwent brain autopsy. Participants received an annual clinical evaluation for up to approximately 10 years, which included detailed cognitive testing and neurological exams.
Participants also answered questions about purpose in life, the degree to which one derives meaning from life’s experiences and is focused and intentional. Brain plaques and tangles were quantified after death. The authors then examined whether purpose in life slowed the rate of cognitive decline even as older persons accumulated plaques and tangles.

What the study suggests is that doing something creative or goal-oriented that requires some effort to start, develop and complete a project helps stave off some of the physiological problems that are seen in Alzheimer’s and other senility-related ailments. Obviously TV watching isn’t goal-oriented.

The study didn’t look at or correlate other studies that have shown how reading stimulates brain activity and also helps ward off dementia and senility. Which is unfortunate, because I believe the two have an obvious relationship. Reading is probably the most powerful activity you can do to keep your brain active and engaged.

The start, I suggest, to developing goals and purpose, is to turn off the TV. The next step is to find something creative to do. Build a deck. Plan a garden. Paint a room. Write a blog. Take photographs. Learn a new word or a new language. Play a game of chess or backgammon. Do a jigsaw puzzle. Play a musical instrument (or learn one). Train your dog to do a trick. Better yet, train your cat.

Do something active, something with a goal, a focus. It doesn’t have to be very big, or exciting or momentous. As long as you get off the couch and away from the TV.

At the very least, read a book. Books will give you ideas, goals, will inspire you, tease your imagination and make you smarter, wiser, more cultured and better looking (okay, maybe not the last one). Books will serve you much better than TV ever will. You don’t have to give up TV for good; just share your time with things that make you smarter, better, wiser, more educated, more intelligent and less prone to dementia than TV.

Just lay off the self-help books. Once you wean yourself from the TV you’ll probably find that tour life has a lot of purpose and meaning and you won’t need the self-help gurus.

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Flatulent dinosaurs warmed ancient earth


Dino fartAn amusing story on Science Daily says researchers have determined that the giant, herbivorous sauropods of the Mesozoic might have been responsible for the era’s warm climate. Well, not the dinosaurs themselves, but rather the methane-producing bacteria in their guts:

“A simple mathematical model suggests that the microbes living in sauropod dinosaurs may have produced enough methane to have an important effect on the Mesozoic climate,” said Dave Wilkinson of Liverpool John Moores University. “Indeed, our calculations suggest that these dinosaurs could have produced more methane than all modern sources — both natural and man-made — put together.”

So basically, dinosaur farts created global warming. That would be one stinky environment.

Wilkinson, Ruxton, and Nisbet therefore calculate global methane emissions from sauropods to have been 520 million tons (520 Tg) per year, comparable to total modern methane emissions. Before industry took off on modern Earth about 150 years ago, methane emissions were roughly 200 Tg per year. By comparison, modern ruminant animals, including cows, goats, giraffes, and others, produce methane emission of 50 to 100 Tg per year.

Out-gassing animals have been blamed before as the cause of our recent climate changes. According to this site,

According to the Food and Agriculture Organization of the United Nations (FAO) agriculture is responsible for 18% of the total release of greenhouse gases world-wide (this is more than the whole transportation sector). Cattle-breeding is taking a major factor for these greenhouse gas emissions according to FAO. Says Henning Steinfeld, Chief of FAO’s Livestock Information and Policy Branch and senior author of the report: “Livestock are one of the most significant contributors to today’s most serious environmental problems. Urgent action is required to remedy the situation.”

The site’s conclusion is to “Eat less meat and dairy products.” Now if dinosaurs did better in the hotter climate of the Mesozoic, then curiously the same advice would have been suitable for carnosaurs, because eating the sauropods could have reduced the global climate. Fewer herbivores equals fewer farts equals less methane in the atmosphere equals cooler temperatures. Somehow I can’t see a T. Rex nibbling on the Cretaceous equivalent of broccoli in order to keep a warmer neighbourhood.

Just another example of the wonderful delights we find in the world of science.

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